The Women’s Omloop Het Nieuwsblad will run without defending champion Marianne Vos (Visma-Lease a Bike) in 2025 or podium companions Lotte Kopecky (SD Worx-ProTime) and Elisa Longo Borghini (UAE Team ADQ).
Lorena Wiebes (SD Worx-Protime) will don bib number 1 on the start list.
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